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DR. KOMAL THAPA
ASSISTANT PROFESSOR

komal.thapa@chitkarauniversity.edu.in

Expert Areas : The areas of research are in-vitro, vivo preclinical studies of CNS disorders such as stroke, Parkinson’s, and Alzheimer’s and renal condition such as Renal ischemia/reperfusion injury.

Dr. Komal Thapa working as an Assistant Professor at School of Pharmacy, Chitkara University, Himachal Pradesh, Solan since August, 2018 with total experience of 5 years in academics and research. She is motivated, self-determined and organized pharmaceutical research professional. She completed her Bachelor of Pharmacy from Rayat Institute of Pharmacy, Ropar, Punjab in 2016 and her Master in Pharmacology from Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab in 2018 and she completed her Ph.D. in Pharmaceutical Science from Chitkara College of Pharmacy, Chitkara University, Rajpura, Punjab in 2023. She has 30 publications in various National/International journals of repute with 843 citations and an h-index of 9. She has also presented 1 review and 1 research paper at an international conferences. She has filled 9 patents, out of which 3 patents have been granted. She has published 6 book chapters. The areas of research are in-vitro, vivo preclinical studies of CNS disorders such as stroke, Parkinson’s, and Alzheimer’s and renal disorders like Renal ischemia/reperfusion injury.

  • Research
  • Patents
  • Education
  • Service

Publications

  • Thapa K, Shivam K, Khan H, Kaur A, Dua K, Singh S, Singh T. G. (2023). Emerging Targets for Modulation of Immune Response and Inflammation in Stroke. Neurochemical Research 2023:1663-1690.
  • Kanojia, N., Thapa, K., Verma, N., Rani, L., Sood, P., Kaur, G., … & Kumar, J. (2023). Update on mucoadhesive approaches to target drug delivery in colorectal cancer. Journal of Drug Delivery Science and Technology, 104831.
  • Thapa K, Khan H, Kanojia N, Singh TG, Kaur A, Kaur G. Therapeutic Insights on Ferroptosis in Parkinson’s disease. European Journal of Pharmacology. 2022 Jul 2:175133.
  • Verma N, Arora V, Awasthi R, Chan Y, Jha NK, Thapa K, Jawaid T, Kamal M, Gupta G, Liu G, Paudel KR. Recent developments, challenges and future prospects in advanced drug delivery systems in the management of tuberculosis. Journal of Drug Delivery Science and Technology. 2022 Aug 12:103690.
  • Thapa K, Singh TG, Kaur A. Targeting ferroptosis in ischemia/reperfusion renal injury. Naunyn-Schmiedeberg’s Archives of Pharmacology. 2022 Aug 3:1-1.
  • Khan H, Garg N, Singh TG, Kaur A, Thapa K. Calpain inhibitors as potential therapeutic modulators in neurodegenerative diseases. Neurochemical Research. 2022 Jan 4:1-25.
  • Thapa K, Grewal AS, Kanojia N, Rani L, Sharma N, Singh S. Alcoholic and non-alcoholic liver diseases: Promising molecular drug targets and their clinical development. Current Drug Discovery Technologies. 2021 Mar 1; 18(3):333-53.
  • Rani L, Thapa K, Kanojia N, Sharma N, Singh S, Grewal AS, Srivastav AL, Kaushal J. An extensive review on the consequences of chemical pesticides on human health and environment. Journal of Cleaner Production. 2021 Feb 10; 283:124657.
  • Kanojia N, Singh S, Singh J, Sharma N, Grewal AS, Rani L, Thapa K, Arora S. Recent advancements and applications of inhalable microparticles based drug delivery systems in respiratory disorders. Biointerface Res App. 2021; 11:10099-118. Thapa K, Singh TG, Kaur A. Cyclic nucleotide phosphodiesterase inhibition as a potential therapeutic target in renal ischemia reperfusion injury. Life Sciences. 2021 Oct 1; 282:119843.
  • Thapa K, Khan H, Singh TG, Kaur A. Traumatic brain injury: mechanistic insight on pathophysiology and potential therapeutic targets. Journal of Molecular Neuroscience. 2021 Sep;71(9):1725-42.
  • Khan H, Singh A, Thapa K, Garg N, Grewal AK, Singh TG. Therapeutic modulation of the phosphatidylinositol 3-kinases (PI3K) pathway in cerebral ischemic injury. Brain Research. 2021 Jun 15; 1761:147399.
  • Thapa K, Khan H, Sharma U, Grewal AK, Singh TG. Poly (ADP-ribose) polymerase-1 as a promising drug target for neurodegenerative diseases. Life Sciences. 2021 Feb 15; 267:118975.
  • Thapa K, Verma N, Singh TG, Grewal AK, Kanojia N, Rani L. COVID-19-Associated acute respiratory distress syndrome (CARDS): Mechanistic insights on therapeutic intervention and emerging trends. International Immunopharmacology. 2021 Dec 1; 101:108328.
  • Grewal S, Sharma N, Singh S, Kanojia N, Thapa K, Swami R, Rupanshi G. Molecular Docking Guided Screening of Phenolic Compounds from Ginkgo Biloba as Multi-Potent Anti-Alzheimer’s Agents. Plant Arch. 2020;20(2):3297-308.
  • Grewal AS, Thapa K, Kanojia N, Sharma N, Singh S. Natural compounds as source of aldose reductase (AR) inhibitors for the treatment of diabetic complications: A Mini Review. Current Drug Metabolism. 2020 Dec 1;21(14):1091-116.
  • Grewal AS, Thapa K, Sharma N, Singh S, Singh R, Singh K, Arora S. Pde4 inhibition: An emerging therapeutic strategy in liver diseases. Plant Archives. 2020;20(2):2285-90.
  • Grewal AS, Thapa K, Bansal A, Sharma N, Singh S. Therapeutic role of nuclear factor erythroid-2 related factor 2 (Nrf2) in liver disorders. Research Journal of Pharmacy and Technology. 2020;13(8):3952-6.
  • Grewal AS, Thapa K, Sharma N, Singh S. New Delhi metallo-β-lactamase-1 inhibitors for combating antibiotic drug resistance: recent developments. Medicinal Chemistry Research. 2020 Aug;29(8):1301-20.
  • Grewal AS, Singh S, Sharma N, Thapa K. New Delhi metallo-β-lactamase-1 inhibitors: a review of the patent literature (2013-2019). Plant Archives. 2020;20(1):3321-8.
  • Grewal S, Sharma N, Singh S, Kanojia N, Thapa K, Swami R, Rupanshi G. Molecular Docking Guided Screening of Phenolic Compounds from Ginkgo Biloba as Multi-Potent Anti-Alzheimer’s Agents. Plant Arch. 2020;20(2):3297-308.

Book Chapter Published

  • Verma, N., Thapa, K., Kanojia, N., Kaur, G., Sood, P., & Dua, K. (2023). Deciphering New Drug Targets in Alzheimer’s Disease. In Deciphering Drug Targets for Alzheimer’s Disease (pp. 1-18). Singapore: Springer Nature Singapore.
  • Verma, N., Thapa, K., & Dua, K. (2021). Material and strategies used in oncology drug delivery. In Advanced Drug Delivery Systems in the Management of Cancer (pp. 47-62). Academic Press.
  • Verma N, Thapa K, Kanojia N, Dureja H, Dua K. Advanced drug delivery systems targeting metabolic disorders: erythropoietic protoporphyria. In Drug Delivery Systems for Metabolic Disorders 2022 Jan 1 (pp. 85-95). Academic Press.
  • Verma N, Thapa K, Dua K. Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects. Microbiome in Inflammatory Lung Diseases. 2022:339-58.
  • Verma N, Thapa K, Dua K. Future Prospects and Challenges in Targeting Cellular and Molecular Mechanisms in Respiratory Diseases. Targeting Cellular Signalling Pathways in Lung Diseases. 2021:903-26.
  • Verma, N., Kanojia, N., Puri, V., Sharma, A., Thapa, K., Rani, L., … & Dua, K. (2023). Advanced nanoparticulate system for the treatment of anti-inflammatory diseases. In Recent Developments in Anti-Inflammatory Therapy (pp. 163-169). Academic Press.

 Books Edited

  • Verma, N., Thapa, K., Kanojia, N., Kaur, G., Sood, P., & Dua, K. (2023). Deciphering New Drug Targets in Alzheimer’s Disease. In Deciphering Drug Targets for Alzheimer’s Disease (pp. 1-18). Singapore: Springer Nature Singapore.
  • Verma, N., Thapa, K., & Dua, K. (2021). Material and strategies used in oncology drug delivery. In Advanced Drug Delivery Systems in the Management of Cancer (pp. 47-62). Academic Press.
  • Verma N, Thapa K, Kanojia N, Dureja H, Dua K. Advanced drug delivery systems targeting metabolic disorders: erythropoietic protoporphyria. In Drug Delivery Systems for Metabolic Disorders 2022 Jan 1 (pp. 85-95). Academic Press.
  • Verma N, Thapa K, Dua K. Microbiome in Inflammatory Lung Diseases: Challenges and Future Prospects. Microbiome in Inflammatory Lung Diseases. 2022:339-58.
  • Verma N, Thapa K, Dua K. Future Prospects and Challenges in Targeting Cellular and Molecular Mechanisms in Respiratory Diseases. Targeting Cellular Signalling Pathways in Lung Diseases. 2021:903-26.
  • Verma N, Thapa K, Dua K. Future Prospects and Challenges in Targeting Cellular and Molecular Mechanisms in Respiratory Diseases. Targeting Cellular Signalling Pathways in Lung Diseases. 2021:903-26.
  • Verma, N., Kanojia, N., Puri, V., Sharma, A., Thapa, K., Rani, L., … & Dua, K. (2023). Advanced nanoparticulate system for the treatment of anti-inflammatory diseases. In Recent Developments in Anti-Inflammatory Therapy (pp. 163-169). Academic Press.
  • Patent titled “CLEANFONO MOBILE COVER has been filed at the Indian Patent Office on 27 July, 2023 with design application no. DPIPCON230801-1313.
  • Patent entitled “System and Device for Smart Digital Thermometer” application no. 202211023378 has been successfully filed at the Indian patent office on 20 April 2022.
  • Patent entitled “Breakage Resistant Cleaning Bar” application no. 202111023871 has been successfully filed at the Indian patent office on 28 May 2021.

Patent Granted

  • Design patent entitled “Heating-based two-way shock avoidance apparatus” has been registered in the Indian patent office with design no. 354988-001.
  • Design patent entitled “Elevated and Conditioned Avoidance Anti-Psychotic Apparatus” has been registered in the Indian Patent Office with design no.354976-0001.
  • Ph.D. Project Research Chitkara University, Punjab, India. Ph.D. thesis on the topic entitled “Exploring Novel Pharmacological Approaches to Attenuate Ischemia-Reperfusion-Induced Renal Injury.” Co-Supervisor: Dr. Amarjot Kaur Grewal, Punjabi University, Patiala. Supervisor: Dr. Thakur Gurjeet Singh Jhajj, Chitkara University, Punjab.
  •  M.Pharmacy (2016 to 2018) Chitkara College of Pharmacy, Chitkara University, Patiala, Punjab, India. Masters in Pharmacology on the topic entitled “Aurintricarboxylic acid mitigates Renal I/R injury in rats.”
  • B.Pharmacy (2012 to 2016) Rayat Institute of Pharmacy, Rayat College, Ropar,  Punjab, India (65%).

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

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